Currently Clinical Views on Genetics of Wilson's Disease

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Currently Clinical Views on Genetics of Wilson's Disease

OBJECTIVE The objective of this study was to review the research on clinical genetics of Wilson's disease (WD). DATA SOURCES We searched documents from PubMed and Wanfang databases both in English and Chinese up to 2014 using the keywords WD in combination with genetic, ATP7B gene, gene mutation, genotype, phenotype. STUDY SELECTION Publications about the ATP7B gene and protein function ass...

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Cholesterol gallstone disease, one of the commonest digestive diseases in western countries, is induced by an imbalance in cholesterol metabolism, which involves intestinal absorption, hepatic biosynthesis, and biliary output of cholesterol, and its conversion to bile acids. Several components of the metabolic syndrome (e.g., obesity, type 2 diabetes, dyslipidemia, and hyperinsulinemia) are als...

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The role of genetics in alzheimer’s disease

Alzheimer's disease is a progressive neurological disorder that causes the brain to shrink (atrophy) and brain cells die. Alzheimer's disease is the most common cause of dementia and causes a decrease in thinking skills and social behaviors. Alzheimer's disease is more common in people over 65 years old. The risk of developing Alzheimer's disease and other types of dementia increases with age,...

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Clinical Genetics of Alzheimer's Disease

Alzheimer's disease (AD) is the most common progressive neurodegenerative disease and the most common form of dementia in the elderly. It is a complex disorder with environmental and genetic components. There are two major types of AD, early onset and the more common late onset. The genetics of early-onset AD are largely understood with mutations in three different genes leading to the disease....

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clinical and para clinical manifestations of 84 cases of wilsons disease

clinical and para clinical manifestations of 84 cases of wilsons disease

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ژورنال

عنوان ژورنال: Chinese Medical Journal

سال: 2015

ISSN: 0366-6999

DOI: 10.4103/0366-6999.159361